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Updated: Jun 16, 2025

Investigating Target Gene Function in a CD40 Agonistic Antibody-induced Colitis Model using CRISPR/Cas9-based Technologies
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罕见的遗传变异为IgG4相关疾病中的免疫失衡提供了机制基础

Dominic J Ciavatta

    The Journal of clinical investigation
    |August 15, 2024
    PubMed
    概括

    在IgG4相关疾病 (IgG4-RD) 的家族中发现了IKZF1和UBR4的单基变异. 这些遗传发现为自身免疫性疾病提供了新的见解.

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