在怀孕期间每天口服铁补充剂
Julia L Finkelstein1, Anna Cuthbert2, Jo Weeks2
1Division of Nutritional Sciences, Cornell University, Ithaca, New York, USA.
The Cochrane database of systematic reviews
|August 15, 2024
概括
在怀孕期间每天口服铁补充剂可能会减少母亲的贫血和铁缺乏症. 然而,其他母亲和婴儿后果的证据是不确定的,需要对铁的进一步研究.
科学领域:
- 产科和妇科 产科和妇科
- 母婴健康 孕产妇和婴儿健康
- 营养科学 营养科学
背景情况:
- 建议在怀孕期间使用铁和叶酸,以预防贫血.
- 补充剂也可以改善母亲,怀孕和婴儿的结果.
研究的目的:
- 为了评估每日口服铁补充剂在怀孕期间的影响.
- 评估铁单独或与叶酸或其他维生素/矿物质结合,作为产前护理干预措施.
主要方法:
- 随机和准随机对照试验的系统审查和元分析.
- 搜索了多个数据库,包括Cochrane怀孕和分娩试验注册表,MEDLINE,Embase和clinicalTrials.gov.gov.
- 使用GRADE方法评估试验资格,偏差风险和数据提取.
主要成果:
- 补充铁可能会减少孕产妇的贫血和铁缺乏症 (中度至低确定性证据).
- 补充铁可以减少出生时体重低的婴儿 (中等确定性证据).
- 关于其他母亲和婴儿后果的证据,包括不良影响和新生儿后果,是不确定的或显示的差异很小.
结论:
- 在怀孕期间每天口服补充铁似乎有利于减少母亲的贫血和缺铁.
- 需要进一步的研究来澄清补充铁对更广泛的母亲和婴儿健康结果的影响.
- 补充铁和叶酸在产前护理中的作用需要继续调查.
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