情感孤独与华盛顿-巴尔的摩地区艾滋病毒感染者老年人的客观认知功能有关:一个横截面研究
Moka Yoo-Jeong1, Raha M Dastgheyb, Eran F Shorer
1Moka Yoo-Jeong, PhD, RN, is an Assistant Professor, School of Nursing, Bouvé College of Health Sciences, Northeastern University, Boston, Massachusetts, USA. Raha M. Dastgheyb, PhD, is an Assistant Professor, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Eran F. Shorer, MD, MSc, is a Postdoctoral Research Fellow, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Cornelia Demsky, BA, is a Senior Research Coordinator, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Olivia Fox, BS, BA, is a Research Program Director, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Divya Inaganti, is an Medical Student, The University of Texas Southwestern Medical School, Dallas, Texas, USA. Sarah Kanner, BS, is a Clinical Research Program Coordinator, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Ava G. Neijna, BA, is a Clinical Research Assistant, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Alison Buchholz, PhD, is an Assistant Professor, Department of Neurology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Tracey E. Wilson, PhD, is Distinguished Service Professor of the Department of Community Health Sciences and Vice Dean for Faculty Affairs and Research, Downstate Health Sciences University, Brooklyn, New York, USA. Leah H. Rubin, PhD, MA, MPH, is a Professor, Department of Neurology, Department of Psychiatry and Behavioral Sciences, Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine and Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
情感上的孤独,而不是社会上的孤独,与艾滋病毒感染的老年人认知功能恶化有关. 这凸显了有针对性的干预措施的必要性,以支持这一群体中的大脑健康.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
背景情况:
- 孤独是健康不良结果的重要危险因素,包括认知能力下降.
- 由于各种生活压力因素,艾滋病毒感染的老年人 (OPWH) 可能特别容易受到孤独的影响.
- 了解孤独的特定亚型及其对认知的影响对于有针对性的干预至关重要.
研究的目的:
- 检查50岁及以上的OPWH中社会和情感孤独与认知表现之间的关系.
- 调查抑郁症状是否调解或缓解孤独与认知之间的关联.
- 为了告知临床策略,旨在保护这个人口中的认知功能.
主要方法:
- 这是一项涉及42名OPWH (≥50岁) 参与者 (平均年龄61.5岁,48%男性,74%黑人) 的横截面研究.
- 参与者完成了De Jong Gierveld孤独量表 (衡量社会和情感孤独) 和认知评估 (数字符号,CalCAPTM).
- 使用患者健康问卷 (PHQ-9) 评估抑郁症状;使用线性回归分析数据,调整社会人口统计和PHQ-9分数.
主要成果:
- 情绪和社会孤独的平均分数分别为1.24 (SD=1.22) 和1.21 (SD=1.14).
- 在调整了社会人口统计学因素和抑郁症状后,情绪孤独与较差的客观认知表现有显著的关联.
- 具体来说,情感孤独与处理速度 (Digit Symbol) 和执行功能 (CalCAPTM) 的缺陷相关,而社会孤独没有显示出明显的关联.
结论:
- 情感孤独与社会孤独不同,与艾滋病毒感染的老年人认知功能受损有关.
- 这些发现强调了在临床实践中解决情绪孤独的重要性,以潜在地减轻OPWH的认知衰退.
- 未来的研究应该探索纵向关联,以及针对情绪孤独的干预措施对这一群体认知健康的有效性.
相关概念视频
Cognitive Development During Adulthood
Negative and Cognitive Symptoms of Schizophrenia
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Relationship Formation
Erikson's Theory on Socioemotional Development during Adulthood
Intimacy Versus Isolation in Early Adulthood
Individuals in early...


