美国卫生系统中铁缺乏症解决方案和解决方案的时间
Jacob C Cogan1, Julia Meyer2, Ziou Jiang3
1Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN.
Blood advances
|August 15, 2024
概括
许多患有铁缺乏症的人在三年内无法达到解决方案. 诸如年龄较大,男性性别和静脉铁治疗等因素有助于提高分辨率,而女性性别和黑人种族与较差的结果有关.
科学领域:
- 临床医学 临床医学
- 血液学 血液学 血液学
- 公共卫生 公共卫生
背景情况:
- 缺铁 (ID) 是一个全球性的健康问题,除了贫血之外,它对健康有重大影响,影响认知和运动.
- 解决实验室诊断的铁缺乏症的典型时间表仍未确定.
- 了解ID解决方案对于公共卫生干预至关重要.
研究的目的:
- 定义从实验室诊断到铁缺乏症解决的时间.
- 确定影响铁缺乏症解决的因素.
- 评估铁缺乏解决的比例和预测因素.
主要方法:
- 来自明尼苏达州全州卫生系统 (2010-2020) 的电子医疗记录的回顾性审查.
- 纳入标准:患有ID的患者 (费里≤25 ng/mL) 和至少一个随访费里水平在3年内.
- 分辨率定义为随后的费里水平≥50 ng/mL;使用时间到事件分析.
主要成果:
- 确定了13,084名ID患者;41.9%的患者在3年内实现了解决,而58.1%的患者没有记录的解决.
- 解决方案的中位时间为1.9年;增加解决方案可能性的因素包括年龄≥60岁,男性性别和静脉注射铁治疗.
- 黑人种族和女性性别与ID解决的可能性较低有关.
结论:
- 很大一部分患者经历了持续的铁缺乏症,其缓解时间延长.
- 需要有针对性的干预措施来改善铁缺乏症的及时诊断和有效治疗.
- 解决女性和黑人个人在ID解决方面的差异至关重要.
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