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头发和头皮的微量元素与动脉样硬化在冠状动脉疾病中的位置有关吗?

Tomasz Urbanowicz^1,2, Anetta Hanć³, Julia Frąckowiak⁴

¹Cardiac Surgery and Transplantology Department, Poznan University of Medical Sciences, Dluga ½ Street, 61-701, Poznan, Poland. turbanowicz@ump.edu.pl.

Biological trace element research

|August 15, 2024

概括

头发皮上的微量元素与特定的冠状动脉疾病位置相关. 这一发现可能将微量元素水平与动脉样硬化发展及其特定的心上动脉参与联系起来.

科学领域:

心血管医学心血管医学
微量元素研究微量元素研究
动脉样硬化病理生理病理学

背景情况:

冠状动脉疾病 (CAD) 是一个主要的健康问题,已知遗传,临床和生活方式的风险因素.
在CAD中表心动脉参与的具体位置仍然不清楚.
动脉样硬化是一种可能受到微量元素影响的炎症反应.

研究的目的:

调查头发和头皮的微量元素度与冠状动脉中的动脉硬化斑块的位置之间的关系.
探索微量元素是否可以作为特定CAD位置的指标.

主要方法:

在175名接受冠状动脉血管造影的患者头发皮的微量元素度 (Ni, Zn, Sb, Cr, Na, As, Mo, Sr, K, Mg) 的分析.
微量元素含量与特定冠状动脉 (左主动脉,左下降动脉, circumflex,右冠状动脉) 中的灯膜狭窄率的相关性.

主要成果:

在左主动脉斑块和 (Ni), (Zn) 和 (Sb) 之间发现了正相关性.
左下垂动脉疾病与 (Cr), (Na), (As) 和 (Mo) 有正相关,与 (Sr) 有负相关.
环动脉病变与Na,K,Cr,Ni,As相关,与Sr相对负相关.
右冠状动脉疾病与 (Mg) 和 Sr. 呈现负相关性.

结论:

头发皮的微量元素度与特定的冠状动脉疾病的位置和严重程度有关.
这些发现表明微量元素与动脉样硬化的局部炎症过程之间存在潜在联系.
微量元素可能是理解冠状动脉局部化在动脉样硬化中的病理生理学基础的缺失环节.

关键词:

动脉样硬化的位置冠状动脉疾病是一种冠状动脉疾病.头发头发头发头发头发在ICP-MS中,使用的是ICP-MS.头发皮肤头发皮肤微量元素中的微量元素.

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