睡眠量,失眠和肺癌风险之间的关联 - 一项系统性审查和元分析
Brian Sheng Yep Yeo1, Jin Hean Koh1, Bryan Yichong Shi1
1Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Sleep & breathing = Schlaf & Atmung
|August 15, 2024
概括
短时间或长时间的睡眠时间和失眠与更高的肺癌风险有关. 这一系统性审查强调了健康睡眠习惯对于潜在降低癌症发病率的重要性.
科学领域:
- 在瘤学瘤学.
- 睡眠医学 睡眠医学
- 流行病学 流行病学
背景情况:
- 关于睡眠特征和肺癌风险的现有研究存在矛盾.
- 需要对当前证据进行全面的综合分析,以澄清这些关联.
研究的目的:
- 系统地审查和综合睡眠时间和失眠与肺癌发病率之间的联系.
- 为了更清楚地了解睡眠模式如何影响患肺癌的风险.
主要方法:
- 在PubMed,Embase和Cochrane图书馆进行了系统的搜索,截至2023年4月23日.
- 来自11项涉及500多万患者的观察性研究的危险比率和几率比率的元分析.
- 使用纽卡斯尔-太华尺度进行偏差风险评估.
主要成果:
- 较短的睡眠时间 (11%的风险增加) 和较长的睡眠时间 (16%的风险增加) 都与更高的肺癌风险有关.
- 失眠症状与肺癌风险增加9%有关.
- 聚合分析包括11项研究,共有5,049,141名参与者.
结论:
- 睡眠不足,过度睡眠和失眠可能会增加肺癌的风险.
- 医疗保健提供者应在患者护理中考虑睡眠习惯,并鼓励健康的睡眠习惯.
- 需要进一步研究客观的睡眠测量和更长的随访时间.
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