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Updated: Jun 16, 2025

Studying RNA Interactors of Protein Kinase RNA-Activated during the Mammalian Cell Cycle
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Published on: March 5, 2019

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在dsRNA上的ADAR1 dsRBD3-PKR激酶域相互作用抑制了PKR激活

Ketty Sinigaglia1, Anna Cherian1, Qiupei Du1

  • 1Central European Institute for Technology at Masaryk University (CEITEC MU), Building E35, Kamenice 735/5, 625 00 Brno, Czechia; National Centre for Biomolecular Research, Faculty of Science, Masaryk University, Kamenice 5, 625 00 Brno, Czechia.

Cell reports
|August 15, 2024
PubMed
概括

作用于RNA 1 (ADAR1) 的腺胺酶抑制蛋白激酶R (PKR) 激活,防止小鼠的胚胎死亡. 这种相互作用对于通过调节干扰素反应来维持肠道完整性和长期生存至关重要.

关键词:
在ADARRNA编辑过程中.阿达尔突变的突变者艾卡迪-古蒂埃雷斯综合征 (AGS) 是一种科普:分子生物学 分子生物学黑手联盟的黑手联盟dsRNARNA是什么意思dsRNA结合蛋白是一种dRNA结合蛋白.天生的免疫传感器.蛋白质激酶R的蛋白质激酶R.

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