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Updated: Jun 16, 2025

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
04:01

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics

Published on: March 15, 2024

906

溶解体铁的积累和随后的溶解体-线粒体铁传递介于PFOS诱导的肝细胞铁亡

Jixun Li1, Ruzhen Feng1, Wei Yang1

  • 1Environment and Occupation Health Department, Dalian Medical University, 9 Lushun South Road, Dalian, China.

Ecotoxicology and environmental safety
|August 15, 2024
PubMed
概括

perfluorooctane sulfonate (PFOS) 通过破坏溶酶体和线粒体铁运输,导致肝细胞铁过载和铁. 自和TRPML1-VDAC3相互作用是这个过程中的关键调节者.

关键词:
铁化是铁化的一种.Lysosomal 铁体中的铁体.线粒体铁是线粒体中的铁.在PFOS系统中,我们可以暂时的受体潜在的粘脂素1 1取决于电压的离子选择性通道3

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