[瘤学的脆弱性:临床实践的更新建议]
Valentin Goede1, Ulrich Wedding2
1Abteilung für Onkologische Geriatrie, Cellitinnen-Krankenhaus St. Marien, Köln, Deutschland.
Deutsche medizinische Wochenschrift (1946)
|August 15, 2024
概括
老年癌症患者的脆弱性增加了风险. 老年评估 (GA) 和量身定制的干预措施提高了治疗耐受性,导致美国临床瘤学会 (ASCO) 更新的指导方针推实用老年评估 (PGA) 工具.
科学领域:
- 老年医学 老年医学
- 在瘤学瘤学.
- 临床实践指南 临床实践指南
背景情况:
- 虚弱是衰老的条件,增加不良结果的风险,特别是在接受治疗的老年癌症患者中.
- 癌症治疗起到压力作用,加剧脆弱性,导致治疗并发症,住院和跌倒的比例更高.
- 目前的证据表明,老年评估 (GA) 和随后的治疗调整可以提高老年人癌症治疗的可行性和耐受性.
研究的目的:
- 审查最近在接受癌症治疗的老年人虚弱的评估和管理方面的进展.
- 要突出更新的美国临床瘤学会 (ASCO) 临床实践指南.
- 为例行临床实施引入"实用老年病学评估" (PGA) 工具.
主要方法:
- 对接受全身治疗的老年癌症患者最近随机对照试验的综述.
- 对接受癌症治疗的老年人更新的ASCO临床实践指南的分析.
- 描述实用老年医学评估 (PGA) 工具的背景和关键方面.
主要成果:
- 老年评估 (GA) 随后的瘤治疗调整和脆弱性干预改善了癌症治疗的耐受性和可行性.
- 美国临床瘤学会 (ASCO) 更新了针对接受癌症治疗的老年人管理脆弱性的指导方针.
- 更新的指南建议"实用老年病学评估" (PGA) 工具用于常规临床使用.
结论:
- 虚弱显著影响老年癌症患者,增加不良事件和治疗并发症的风险.
- 综合老年评估 (GA) 和干预措施对于优化老年人癌症护理至关重要.
- 建议使用实用老年评估 (PGA) 工具,以促进在常规瘤实践中实施基于GA的护理.
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