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Updated: Jun 16, 2025

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一种定量LC-MS/MS方法用于调查涉及海洛因和可卡因的多种物质使用情况

Huimei Wei1, Jing Deng1, Ting Zhang1

  • 1Molecular Modeling and Biopharmaceutical Center, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, KY 40536, USA; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, KY 40536, USA.

Journal of pharmaceutical and biomedical analysis
|August 15, 2024
PubMed
概括

同时使用海洛因和可卡因,或速度球,增加了过量致死风险. 海洛因减缓了可卡因的排泄,而可卡因加快了海洛因的新陈代谢,影响了药物相互作用和致命的结果.

关键词:
这是可卡因可卡因.这是海洛因.这是LC-MS/MS.代谢过程中的代谢.药理动力学 药理动力学多种物质使用多种物质使用.

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Mass Spectrometry: Complex Analysis01:21

Mass Spectrometry: Complex Analysis

Mass spectrometry is an important technique for the identification of pure compounds. However, it has some limitations for the analysis of complex mixtures, often due to excessive fragmentation making the spectrum too complicated to decipher. Mass spectrometry can be combined with suitable separation methods in sequence, forming hyphenated methods, which are useful in the analysis of complex mixtures.
GC–MS is a powerful hyphenated method commonly used in forensics and environmental...
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