数百万年的基因组静止在地下沉积物中
Arkadiy I Garber1, Gustavo A Ramírez2, Steven D'Hondt3
1Biodesign Institute, School of Life Sciences, Arizona State University, Tempe, Arizona, USA.
Environmental microbiology
|August 15, 2024
概括
埋在海底沉积物深处的微生物在数百万年内表现出了显著的基因组稳定性. 尽管长期休眠,这些古老的Thalassospira血统保持了他们的遗传完整性,挑战了放松选择的想法.
科学领域:
- 微生物学 微生物学
- 进化生物学 进化生物学
- 基因组学就是基因组学.
背景情况:
- 了解深层地下环境中的微生物进化是具有挑战性的.
- 深海沉积物中的微生物面临着种群瓶,可能导致放松的选择和伪基因的形成.
研究的目的:
- 研究古老的地下沉积物中微生物的进化机制和基因组变化.
- 为了测试长期埋葬的微生物血统中放松选择的假设.
主要方法:
- 从300万至600万年前的地下沉积物中分离了Thalassospira菌株.
- 基因组比较分析下地板孤立物和表面居住的亲属.
- 检查跨基因组的选择强度和突变模式.
主要成果:
- 海底Thalassospira分离物在全基因组选择强度方面表现出与表面菌株的血统特异性相似之处.
- 在下层分离物中没有发现放松选择增加或显著基因组变化的证据.
- 埋葬的Thalassospira的基因组似乎在代谢休眠期和长时间的生成期间保持稳定.
结论:
- 海底微生物分离物没有显示放松选择的迹象,这表明几百万年来几乎处于静止状态.
- 独特的基因组特征可能源于过去300万至600万年间地表生活后代的遗传变化.
- 在海底下面的Thalassospira血统表明,在极端条件下,基因组保持稳定.
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