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在中年和晚年成年期进行过导管肺置换

John D'Angelo¹, John Lisko², Vasilis C Babaliaros³

¹Division of Internal Medicine, Emory University School of Medicine, Atlanta, Georgia.

The American journal of cardiology

|August 15, 2024

概括

在40岁以上患有先天性心脏病的成年人中,透气管肺置换 (TPVR) 显示了有利的短期和中期存活率. 然而,右心室功能障碍仍然存在,这表明需要在这个不断增长的患者群体中优化TPVR时间.

科学领域:

心脏病学心脏病学
成年人的先天性心脏病
干预心脏病学干预心脏病学

背景情况:

成人先天性心脏病 (ACHD) 的存活率正在改善,增加了对肺门干预的需求.
透气管肺置换 (TPVR) 是需要肺干预的ACHD患者的常见手术.

研究的目的:

评估40岁及以上患者TPVR的短期和中期临床结果.
在这个特定的年龄组中确定影响TPVR后生存的风险因素.

主要方法:

对67名年龄≥40岁的患者进行了回顾性队列研究,这些患者在2012年至2024年期间接受了TPVR.
使用描述性分析,卡普兰-梅尔生存分析和考克斯比例危险建模.
评估结果包括生存,并发症和右心室功能.

主要成果:

在TPVR的中位数年龄为48岁;中位数随访时间为3.5年.
一年,三年和五年生存率分别为95%,91%,82%.
在TPVR之前的住院状态是生存的显著负预测指标 (HR 24.7,p=0.002).

结论:

在40岁以上的患有ACHD的患者中,TPVR表现出有利的周围手术和中期结果.
右心室功能障碍在TPVR后没有显著改善.
需要进一步的研究来确定TPVR在老年ACHD患者的最佳时间.

关键词:

成年人的先天性心脏病.通过导管更换肺门.

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