生物补充剂对婴儿睡眠和安静行为的影响:系统性审查和元分析
M Matin1, M Brockway2,3,4, A Badejo2
1School of Nursing, Faculty of Health and Social Development, 8166University of British Columbia Okanagan campus, Kelowna, British Columbia, Canada.
Beneficial microbes
|August 15, 2024
概括
生物补充剂,包括益生菌,不会改善婴儿在前四周的睡眠时间. 事实上,到第五周,它可能会略微减少睡眠时间,这表明婴儿睡眠没有好处.
科学领域:
- 儿科 儿科 儿科
- 微生物学 微生物学
- 营养科学 营养科学
背景情况:
- 婴儿肠道微生物群的组成在生命的第一年发生了显著的变化.
- 生物补充剂 (益生菌,益生菌,共生菌,后生物) 可以改变婴儿微生物群.
- 婴儿微生物组可能会影响婴儿的睡眠模式和行为.
研究的目的:
- 系统地审查和分析生物补充剂对满期婴儿 (0-12个月) 睡眠行为的影响.
- 评估生物干预是否会影响婴儿睡眠时间和安静.
主要方法:
- 系统审查和随机对照试验 (RCT) 的元分析发表到2023年6月.
- 在七个数据库中搜索了关于婴儿生物补充剂和睡眠的研究.
- 包括23个涉及453项独特研究的RCT;使用修改后的Cochrane协作工具评估偏差风险.
主要成果:
- 益生菌补充最常见 (53%),其次是益生菌 (28%) 和共生菌 (19%).
- 在益生菌使用的前四周内,没有观察到睡眠时间的显著差异.
- 在接受益生菌的婴儿与安慰剂相比,在第五周观察到睡眠时间的边缘显著减少.
结论:
- 益生菌补充剂在产后前四周内不会提高婴儿睡眠时间.
- 有证据表明,在使用益生菌的第五周,睡眠时间可能会减少.
- 对于其他生物类型和12个月以上婴儿睡眠的长期影响,数据有限.
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