对比的DNA甲基化揭示了鼻对高海拔地区的表观遗传适应
Ling Wang1,2, Wei-Qiang Liu1,2, Juan Du1
1Key Laboratory of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
Zoological research
|August 15, 2024
概括
两个子物种之间的DNA甲基化差异揭示了它们对高海拔的适应. 这些表观遗传变化影响了参与细胞功能和应激反应的基因,为进化过程提供了洞察力.
科学领域:
- 表观遗传学和基因组学
- 进行比较基因组学.
- 进化生物学 进化生物学
背景情况:
- 基因甲基化对于环境适应至关重要.
- 全基因组双硫酸盐测序被用于在云南高海和金色高海中分析DNA甲基化.
- 金鼻子子的DNA甲基化总体水平略高.
相关概念视频
Epigenetic Regulation
3.0K
Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...
X-chromosome...
3.0K
Genomic Imprinting and Inheritance
34.2K
Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
34.2K


