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Updated: Jun 16, 2025

A Robust Single-Particle Cryo-Electron Microscopy cryo-EM Processing Workflow with cryoSPARC, RELION, and Scipion
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在RELION-5中用于电子冷断层扫描的图像处理管道

Alister Burt1,2, Bogdan Toader1, Rangana Warshamanage3,4

  • 1MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, UK.

FEBS open bio
|August 15, 2024
PubMed
概括

我们在RELION-5中开发了一个新的图像处理管道,用于电子断层扫描. 这个工具标准化了从原始电影到原子模型构建的数据分析,改善了宏分子复杂结构的确定.

关键词:
电子显微镜的电子显微镜电子断层扫描是一种电子断层扫描.图像处理是图像处理的过程.软件 软件 软件 软件 软件

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Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
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