通过载体介导的细胞外プロ林的耗尽直接促进了对细菌病原体的植物模式触发免疫力
Conner J Rogan1, Yin-Yuin Pang1, Sophie D Mathews1
1Department of Botany and Plant Pathology, Oregon State University, Corvallis, OR, 97331, USA.
Nature communications
|August 15, 2024
概括
植物利用MAMP诱导的免疫来限制病原体的生长,通过耗尽细菌的营养物质细胞外普罗林来限制病原体的生长. 这个过程需要LHT1转运器,揭示了对病原体的新型防御机制.
科学领域:
- 植物免疫力 植物免疫力
- 微生物的病原发生.
- 植物与微生物的相互作用
背景情况:
- 植物具有检测微生物相关分子模式 (MAMPs) 的免疫受体,以启动防御.
- 通过MAMP诱导免疫 (PTI) 限制病原体生长的机制尚未完全理解.
研究的目的:
- 研究植物如何在MAMP诱导的免疫期间限制病原体的生长.
- 识别特定的分子和途径,参与植物防御细菌病原体.
主要方法:
- 使用了组合的代谢学和遗传学方法.
- 研究了植物排泄的普罗林和氨酸胺转运体1 (LHT1) 的作用.
主要成果:
- 植物排泄的普罗林作为Pseudomonas syringae的毒性信号和营养素.
- 由MAMP诱导的细胞外普罗林的耗尽有助于对P. syringae的PTI.
- 细胞外林的耗尽是由氨基酸载体LHT1.1调解的.
结论:
- 细胞外林的耗尽是植物诱导免疫力的有效组成部分.
- 代谢物,特别是氨基酸的耗尽可能是对微生物病原体的广泛防御策略.
相关概念视频
Defenses Against Pathogens and Herbivores
23.4K
Plants present a rich source of nutrients for many organisms, making it a target for herbivores and infectious agents. Plants, though lacking a proper immune system, have developed an array of constitutive and inducible defenses to fend off these attacks.
23.4K
Cell Signaling in Plants
5.6K
Plant cells communicate to coordinate their cycle of growth, flowering and fruiting, and activities in roots, shoots, and leaves in response to the changing environmental conditions. Plant signaling is distinct from animal signaling. Plants primarily utilize enzyme-linked receptors, whereas the largest class of cell-surface receptors in animals are G-protein coupled receptors (GPCRs). Unlike animals, receptor tyrosine kinases are rare in plants. Instead, plants have a diverse class of...
5.6K
Protein Transport to the Outer Chloroplast Membrane
2.0K
Chloroplast outer membrane proteins encoded by the nucleus are synthesized in the cytosol. Soon after synthesis, they bind cytosolic factors such as 14-3-3 protein and the Hsp70 chaperones that keep these precursors in an unfolded state until their translocation.
Two models describe the mechanism of precursor recognition and entry across the outer membrane through the TOC complex. Model 1 suggests the newly synthesized precursor binds to the TOC receptor 159 and forms a complex.
Two models describe the mechanism of precursor recognition and entry across the outer membrane through the TOC complex. Model 1 suggests the newly synthesized precursor binds to the TOC receptor 159 and forms a complex.
2.0K
Protein Transport to the Inner Chloroplast Membrane
2.1K
Proteins targeted to the inner chloroplast membrane, or plastid proteins, are transported by two general pathways: the stop-transfer and the re-insertion or post-import pathways. Most plastid proteins carry N-terminal transit sequences and internal import sequences targeting it to the specific chloroplast subcompartment. Proteins targeted by the stop-transfer pathway have internal hydrophobic sequences that inhibit their translocation into the stroma. As a result, these precursors are arrested...
2.1K
Protein Transport to the Thylakoids
2.2K
Thylakoids are membrane-bound sac-like structures within the chloroplast that serve as sites for photosynthesis. Thylakoid lumen contains many electron transport proteins and is enclosed by a thylakoid membrane rich in the light-harvesting complex. Proteins targeted to the thylakoids are transported as precursors and are sorted by the general TOC/TIC import pathway. Once the precursor reaches the stroma, stromal processing peptidases remove their transit signal and expose thylakoid signal...
2.2K
Short-distance Transport of Resources
15.8K
Short-distance transport refers to transport that occurs over a distance of just 2-3 cells, crossing the plasma membrane in the process. Small uncharged molecules, such as oxygen, carbon dioxide, and water, can diffuse across the plasma membrane on their own. In contrast, ions and larger molecules require the assistance of transport proteins due to their charge or size. Transport across membranes also occurs within individual cells, playing a variety of essential roles for the plant as a whole.
15.8K


