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Updated: Jun 16, 2025

CIRCLE-Seq for Interrogation of Off-Target Gene Editing
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CIRCLE-Seq for Interrogation of Off-Target Gene Editing

Published on: November 1, 2024

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设计了IscB-ωRNA系统,用于基础编辑扩大了目标范围

Qingquan Xiao1,2, Guoling Li1, Dingyi Han2,3

  • 1HuidaGene Therapeutics Co. Ltd., Shanghai, China.

Nature chemical biology
|August 15, 2024
PubMed
概括

研究人员确定了新的IscB蛋白质用于基编辑,增强一个以扩大其准范围. 这些设计的IscB基编辑器对研究和治疗诸如杜申肌肉发育不良等遗传疾病有前途.

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