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The quantity that describes the deformation of a body under stress is known as strain. Strain is given as a fractional change in either length, volume, or geometry under tensile, volume (also known as bulk), or shear stress, respectively, and is a dimensionless quantity. The strain experienced by a body under tensile or compressive stress is called tensile or compressive strain, respectively. In contrast, the strain experienced under bulk stress and shear stress is known as volume and shear...
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Measurement of Liver Stiffness Using Atomic Force Microscopy Coupled with Polarization Microscopy
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儿童体重特定的正常肝硬度值.

Paul Knebelmann1, Antoine Martin-Champetier2, Anderson Loundou3

  • 1Department of Pediatric and Prenatal Radiology, Hôpital Timone Enfants, APHM, 264 Rue Saint Pierre, 13005, Marseille, France. paul.knebelmann@gmail.com.

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概括

儿科肝硬度,通过二维剪切波弹性学测量,随着孩子的体重显著增加. 这些发现为诊断儿童肝病确立了关键的体重特异性参考值.

关键词:
二维剪切波弹性图形2维剪切波弹性图形肝脏的弹性 肝脏的弹性儿科 儿科 儿科超声波弹性图形学 超声波弹性图形学

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科学领域:

  • 儿科胃肠病学 儿科胃肠病学
  • 医疗成像医学成像
  • 诊断性的超声波检查

背景情况:

  • 二维 (2D) 剪波弹性图是评估肝硬度的非侵入性方法.
  • 关于儿科患者肝硬度及其与体重相关性的数据有限.

研究的目的:

  • 在没有肝病的儿童中建立体重特定的肝硬度参考值.
  • 调查儿科患者的体重与肝脏弹性之间的关联.

主要方法:

  • 对171名接受临床指示超声波的儿童进行了回顾性单一中心研究.
  • 使用佳能医疗系统的Aplio i800和a450设备进行的2D切尔波弹性图.
  • 儿童被分为十个体重组,以分析与体重相关的肝硬度趋势.

主要成果:

  • 肝硬度值显示,随着体重的增加,肝硬度的全球趋势显著增加.
  • 在右和左肝叶硬度测量之间没有发现显著差异.
  • 所有儿科参与者的平均正常肝硬度值为5.3±1.1kPa.

结论:

  • 通过2D剪波弹性学评估的儿科肝硬度与体重正相关.
  • 这些确定的体重特定参考值可以帮助区分儿童的正常肝硬和病态肝硬.