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系统性炎症反应指数作为中风相关肺炎的预测指标,用于通过血栓切除术治疗急性缺血性中风的患者:一项回顾性研究
Feng Zheng1,2, Wen Gao3,4,5, Yinfeng Xiao4,6
1Department of Neurosurgery, the Second Affiliated Hospital, Fujian Medical University, No.34 North Zhongshan Road, Quanzhou, 362000, Fujian Province, China. dr.feng.zheng@gmail.com.
BMC neurology
|August 15, 2024
概括
系统性炎症反应指数 (SIRI) 可以预测急性缺血性中风 (AIS) 患者中风相关肺炎 (SAP) 的风险. 早期识别高风险患者是可能的,如果SIRI值很高.
科学领域:
- 神经学 神经学
- 关键护理医学 关键护理医学
- 生物标志物 生物标志物
背景情况:
- 与中风相关的肺炎 (SAP) 是急性缺血性中风 (AIS) 患者的常见并发症.
- 在接受血栓切除术的AIS患者中预测SAP风险对于及时干预至关重要.
- 这种人群中SAP的全身炎症反应指数 (SIRI) 的预测值尚未得到充分确立.
研究的目的:
- 为了研究SIRI对SAP风险的预测价值在AIS患者治疗血栓切除术.
- 在这个患者队列中开发和验证SAP的预测模型.
主要方法:
- 通过血栓切除术治疗的84名AIS患者的回顾性分析 (2018年8月 - 2022年8月).
- 用多变量逻辑回归和接收器操作特征 (ROC) 曲线分析来评估SIRI的预测能力.
- 通过校准和决策曲线分析,构建并评估预测准确性的名图.
主要成果:
- 在包括的66.7%的患者中,SAP存在.
- 较高的SIRI值与SAP风险增加有显著的关联 (OR=1.169,p=0.014).
- 年龄≥60 (OR=4.076,p=0.024) 和NIHSS得分≥20也是显著的预测因素.
- 纳入SIRI的名录显示出良好的预测准确性 (C指数=0.774).
结论:
- 在接受血栓切除术的AIS患者中,SIRI是SAP的独立预测因子.
- 高SIRI值可以帮助早期识别患有SAP高风险的患者.
- 这一发现支持使用SIRI作为一种有价值的工具来管理AIS患者的血栓切除术后.
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