毒素和家禽中的菌病 - - 同时发生,相互作用和影响
Luis-Miguel Gómez-Osorio1,2, Marko Vasiljevic2, Jog Raj2
1CIBAV Research Group, Facultad de Ciencias Agrarias, Universidad de Antioquia, UdeA, Medellín, Colombia.
Frontiers in veterinary science
|August 16, 2024
概括
鸟类菌病和真菌毒素经常同时发生,使家禽的健康状况恶化. 本综述详细介绍了真菌毒素如何增加对菌病的易感性,影响家禽生产,并需要综合管理策略.
科学领域:
- 兽医科学 兽医科学 兽医科学
- 动物营养 动物营养
- 毒理学 毒理学 毒理学
背景情况:
- 由Eimeria物种引起的鸟类菌病和真菌毒素显著影响全球家禽生产.
- 菌毒素是真菌的二次代谢产物,在家禽料中经常与菌病一起发生,但它们之间的关系尚不清楚.
- 了解这种相互作用对于减轻家禽行业的经济损失至关重要.
研究的目的:
- 综合审查真菌毒素和鸟类菌病之间的复杂关系.
- 阐明各种真菌毒素如何损害家禽的健康并使它们易患艾梅里亚感染.
- 讨论在真菌毒素存在的情况下对菌病的预防和治疗的影响.
主要方法:
- 文献综述综合了当前关于真菌毒素 - 菌病相互作用的知识.
- 分析菌毒素毒性机制,包括免疫抑制和肠道健康破坏.
- 对结合性真菌毒素和菌病挑战的诊断和控制策略的检查.
主要成果:
- 毒素,包括青毒素, ochratoxins,trichothecenes和Fusarium毒素,削弱家禽的免疫力和肠道完整性.
- 菌毒素毒性表现为直接的肠道损伤,营养吸收受损,炎症,氧化应激和改变的肠道微生物群.
- 这些影响加剧了菌病的严重程度,使疾病管理复杂化.
结论:
- 综合严格的料管理,疾病预防和定期监测的整体方法至关重要.
- 有效的策略必须解决菌毒素和菌病对家禽健康和生产力的联合风险.
- 需要进一步的研究才能充分理解和管理家禽养殖中这些相互关联的挑战.
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