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Updated: Jun 16, 2025

Visualization of Endoplasmic Reticulum Subdomains in Cultured Cells
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鉴定内质网膜光线的ERAD依赖性降解子

Rachel Sharninghausen1, Jiwon Hwang1, Devon D Dennison2

  • 1Department of Biological Chemistry, University of Michigan Medical School, 1150 W Medical Center Drive, Ann Arbor, MI 48109, USA.

bioRxiv : the preprint server for biology
|August 16, 2024
PubMed
概括

研究人员发现了第一个源自内质网膜 (ER) 光线的降解子. 这些序列通过ER相关降解 (ERAD) 途径实现向蛋白质降解,扩大治疗策略.

关键词:
欧洲议会 (ERAD) 委员会.Hrd1 无处不在的合酶它们中的一种是S. cerevisiae.有针对性的蛋白质降解降解.我们 degrons degrons.随着内细胞网关联的降解退化.膜蛋白质是膜蛋白质的组成部分.蛋白质质量控制 蛋白质质量控制在任何地方都是无处不在的.

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