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Updated: Jun 16, 2025

Detection of Rare Genomic Variants from Pooled Sequencing Using SPLINTER
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Detection of Rare Genomic Variants from Pooled Sequencing Using SPLINTER

Published on: June 23, 2012

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我们所有人的多样性和规模在情境上改善了多基因预测,对代表性不足的人口进行了最大的改进

Kristin Tsuo1,2,3, Zhuozheng Shi4, Tian Ge2,5,6,7

  • 1Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.

bioRxiv : the preprint server for biology
|August 16, 2024
PubMed
概括

多种基因组数据,包括来自我们所有人研究计划的数据,改善了代表性不足的群体的多基因风险得分 (PRS). 结合不同的数据集可以提高PRS的准确性,特别是对于历史上被排除在基因组研究之外的个体.

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