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Updated: Jun 16, 2025

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协作交叉小鼠创始菌株CAST/EiJ作为致命的COVID-19新型模型的特征

Candice N Baker1, Debra Duso2, Nagarama Kothapalli2

  • 1The Jackson Laboratory.

Research square
|August 16, 2024
PubMed
概括

关注的SARS-CoV-2变种 (VOCs) 感染小鼠,使得对各种COVID-19反应的研究成为可能. 特定的小鼠菌株,如CAST/EiJ,表现出严重的疾病,并可能为治疗开发模拟人类反应.

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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
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