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双特异性抗体参与者用于癌症免疫治疗

Hidde Ploegh1, Xin Liu1, Camille Le Gall2

  • 1Boston Children's Hospital.

Research square
|August 16, 2024
PubMed
概括

针对CTLA-4或PD-L1的两种特异性抗体吸引剂通过招募多种抗体来表现出强大的抗瘤活性. 加强PD-L1与药物或激动剂的接触显著提高了疗效,提供了一种新的免疫检查点阻塞策略.

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