优化局部滴剂的有效性,通过适当的眼定位来优化眼的有效性
Yu Xia1, Nathaniel A Blecher2, Philip L Custer2
1Medical Scientist Training Program, Washington University School of Medicine, St. Louis, MO, 63110, USA.
American journal of ophthalmology case reports
|August 16, 2024
概括
通过手术纠正ectropion,在患有眼内压升高 (IOP) 的患者中改善了局部玻璃眼治疗的疗效. 这一案例表明,盖错位修复可以提高青光眼的药物疗效.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼研究研究 玻璃眼研究
- 眼镜塑料是一种眼镜塑料.
背景情况:
- 青光眼的管理通常涉及局部药物降低眼内压力 (IOP).
- 眼的向外转向 (ectropion) 可以使眼睛表面的健康和药物输送复杂化.
- 提高现有的青光眼治疗疗法的疗效对于患者的治疗结果至关重要.
研究的目的:
- 为了记录ectropion修复对局部玻璃眼治疗的有效性的影响.
- 研究一种潜在的非药理学方法,以提高青光眼治疗结果.
主要方法:
- 一个71岁男性的病例研究,患有青光眼和双侧下眼外皮.
- 顺序的单边手术纠正ectropion. 顺序的单边手术纠正.
- 在手术前和手术后监测眼内压 (IOP) 和对局部玻璃眼药物的反应.
主要成果:
- 尽管医疗和激光治疗,但患者呈现出升高的内压.
- 在每一次单边的ectropion修复后,局部玻璃眼治疗在降低IOP方面变得更有效.
- 在观察期间,没有对青光眼药物或其剂量进行任何改变.
结论:
- 纠正下眼lid ectropion可以显著提高局部玻璃眼瘤药物的疗效.
- 盖的错误位置应被视为影响青光眼治疗有效性的因素.
- 通过手术纠正ectropion可能提供一种新的方法来增强选择的青光眼患者的IOP控制.
相关概念视频
Drug Delivery: Miscellaneous Routes
329
Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection, and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
329
Open Angle Glaucoma: Treatment
413
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
413
Local Anesthetics: Common Agents and Their Applications
420
Local anesthetics (LAs) are commonly used for various applications in medical and dental procedures. Some of the common agents used are cocaine, lidocaine, and bupivacaine.
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
420


