预测COVID-19患者在最初的流行病阶段需要先进的呼吸系统支持:回顾性分析
Tuğba Çiçek1, Melahat Uzel Sener2, Ayperi Öztürk2
1Chest Disease, Konya Numune Hospital, Konya, TUR.
Cureus
|August 16, 2024
概括
年龄,高C反应蛋白 (CRP),费里水平和全身免疫炎症反应指数 (SIRI) 预测了COVID-19患者需要高级呼吸支持 (ARS) 的需要. 早期识别高风险个体对于及时干预和流行病管理至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
- 公共卫生 公共卫生
背景情况:
- 在全球范围内,COVID-19疫情造成了显著的发病率和死亡率.
- 住院COVID-19患者的病情可能会恶化,需要高级呼吸系统支持 (ARS).
- 识别ARS的早期预测因子对于在流行病期间管理患者的结果至关重要.
研究的目的:
- 确定预测COVID-19患者需要ARS的关键风险因素.
- 分析人口统计,临床和实验室数据,用于早期ARS预测.
- 为呼吸系统健康危机管理策略提供信息.
主要方法:
- 对162名COVID-19患者的回顾性研究,这些患者在疫情的前三个月被录取.
- 排除在入院时需要ARS或机械通风的患者.
- 多变量后勤回归和ROC曲线分析以确定ARS的独立预测因素.
主要成果:
- 32.1%的患者需要ARS.
- 相关预测因素包括年龄,C反应蛋白 (CRP) 的升高,费里丁的升高,以及系统性免疫炎症反应指数 (SIRI).
- 在SIRI测试中,AUC值为0.785,预测ARS的截止值为1.915.
结论:
- 年龄,CRP,费里丁和SIRI是COVID-19患者ARS的关键预测因素.
- 早期识别高风险患者可以及时进行干预和资源优化.
- 这些发现支持改善未来呼吸系统健康危机的策略.
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