对酒精使用障碍的简短干预与酒精相关肝脏疾病的住院患者的治疗机会有关
Patrick A Twohig1, Alena Balasanova, Lauren Cooper
1From the Division of Gastroenterology and Hepatology, University of Nebraska Medical Center, Omaha, NE (PAT, LC, ML, NK, WM, MO, TBP); and Department of Psychiatry, University of Nebraska Medical Center, Omaha, NE (AB).
Journal of addiction medicine
|August 16, 2024
概括
对酒精使用障碍 (AUD) 的简短干预显著增加了酒精相关肝病 (ALD) 患者的治疗率. 这种方法改善了无移植生存率,突出了它在ALD护理中的重要性.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 成 药物 药物 药物 药物
- 移植 移植 移植 移植
背景情况:
- 酒精相关性肝病 (ALD) 是美国肝移植的主要原因.
- 对于ALD患者来说,建议对酒精使用障碍 (AUD) 进行治疗,但通常未得到充分利用.
研究的目的:
- 在住院ALD患者中确定AUD治疗的预测因素.
- 评估AUD治疗对30天再入院,恢复饮酒和1年无移植生存时间的影响.
主要方法:
- 对109名患有ALD和AUD住院的患者进行了回顾性队列研究 (2018-2020年).
- AUD治疗定义为药物治疗,住院,门诊或支持小组参与,出院后90天内.
- 排除已死亡或失踪的患者在90天后进行随访.
主要成果:
- 51%的患者接受了AUD治疗;年轻的年龄,胃肠道学/肝病学咨询,成精神病学咨询,以及简短的AUD干预预测了治疗.
- 简短的AUD干预显示了与接受治疗的最强相关性 (AOR,18.19).
- 接受AUD治疗的患者有改善的无移植生存率 (HR,0.44;P=0.04).
结论:
- 对AUD的简短干预与ALD患者的治疗率密切相关.
- 将短暂干预整合到护理中可能会改善AUD治疗率和患者的治疗结果.
- 进一步的研究应侧重于实施和评估ALD人群中AUD的简短干预策略.
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