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青少年移植接收者:神经认知功能概述和对长期结果的影响

Emily M Fredericks^1,2, Kelly E Rea^1,2, Melissa K Cousino^1,2

¹Division of Pediatric Psychology, Department of Pediatrics, Michigan Medicine, Ann Arbor, Michigan, USA.

Pediatric transplantation

|August 16, 2024

概括

青少年实体器官移植接受者面临持续的神经认知风险,特别是在执行职能方面,影响了对成人护理的坚持和过渡. 早期监测神经发育对于应对这些挑战至关重要.

科学领域:

儿科医学儿科医学儿科医学
神经科学是一个神经科学.
移植手术移植手术移植手术

背景情况:

固体器官移植 (SOT) 改善了末期器官疾病的年轻人的生存率.
接受SOT的儿童面临独特的神经发育,认知和学术风险因素.
了解从移植候选人的神经认知发展对于评估早期缺陷至关重要.

研究的目的:

概述青少年移植接受者的神经认知风险和长期结果.
讨论神经认知功能在这个人群中的影响.

主要方法:

这篇论文回顾了有关末期器官功能障碍的青少年神经认知功能现有文献.
它讨论了对青少年移植接受者的影响.

主要成果:

青少年和年轻成年SOT接受者在移植后表现出显著的执行功能障碍.
这种功能障碍影响决策,治疗坚持,以及过渡到成人护理.

结论:

虽然移植可能会减少长期的神经认知风险,但青少年仍然很脆弱,特别是在执行功能方面.
基线和后续神经认知评估对于监测发育,改善坚持和缓解向成人护理过渡至关重要.

关键词:

青春期青春期青春期决策能力决策能力发展发展发展发展发展.神经认知功能的神经认知功能.实体器官移植实体器官移植过渡时期的过渡.

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