在屠宰场的工人中评估通风功能和相关的炎症标志物
Mona Abdallah Ramadan1, Rateba Said Mohammed2, Aisha Safwat Saif Eldin2,3
1Department of Occupational and Environmental Medicine, Faculty of Medicine, Cairo University, Giza, Egypt. dr-monaabdallah@kasralainy.edu.eg.
International archives of occupational and environmental health
|August 16, 2024
概括
屠宰场工人由于工作场所的生物气溶增加了呼吸系统问题和炎症. 随着长时间的就业,他们的肺功能显著下降,这表明职业肺部风险.
科学领域:
- 职业健康 职业健康 职业健康
- 肺部医学 肺部医学
- 环境健康 环境健康
背景情况:
- 肉类加工行业在全球范围广泛,但关于屠宰场工人的职业肺部健康影响的数据很少.
- 了解屠宰场环境对工人呼吸系统健康和相关炎症标志物的影响至关重要.
研究的目的:
- 调查屠宰场大气对暴露工人的呼吸健康的影响.
- 评估屠宰场工人的呼吸习惯和炎症标志物的变化.
主要方法:
- 一项涉及82名非吸烟者 (41名屠宰场工人和41名匹配对照) 的横截面研究.
- 数据收集包括医疗/职业病史问卷,全身检查,呼吸功能测试和血清中白蛋白-6 (IL-6) 和高敏感性C反应蛋白 (hsCRP) 的测量.
主要成果:
- 屠宰场的工人表现出更高的呼吸系统症状和明显减少的呼吸功能参数 (FVC%,FEV1%,FEV1/FVC,FEF 25-75%,PEF%).
- 暴露组中观察到IL-6和hsCRP的血清水平升高,与呼吸功能负相关.
- 较高的IL-6和hsCRP水平与增加的年龄和就业时间有关.
结论:
- 屠宰场工人显示呼吸系统疾病和炎症标志物显著增加.
- 通风功能参数的大幅下降表明与工作场所生物气溶暴露有联系.
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