在实施多模式阿片类药物节约途径之前和之后,单级腰椎微分隔术后的术后阿片类药物消费
Bulletin of the Hospital for Joint Disease (2013)
|August 16, 2024
概括
一个阿片类药物节约途径在腰部微分隔切除术患者的手术后2周减少了25%的阿片类药物处方. 非阿片类止痛药的使用显著增加,表明疼痛管理策略的转变取得了成功.
科学领域:
- 疼痛管理 疼痛管理
- 整形外科手术 整形外科手术
- 药理学 药理学是指药理学的学科.
背景情况:
- 全国阿片类药物危机需要减少阿片类药物依赖.
- 越来越多地寻求非阿片类替代品来治疗疼痛.
- 阿片类药物节约途径旨在减少手术患者的阿片类药物使用.
研究的目的:
- 为了比较出院后的阿片类和非阿片类止痛药处方.
- 评估阿片类药物节约途径对腰部微分隔切除术 (MLD) 患者的有效性.
- 评估在实施途径之前和之后疼痛管理的变化.
主要方法:
- 一项回顾性研究,比较了2018年9月1日之前和之后的MLD患者.
- 两个队列:实施前 (n=100) 和实施后 (n=100).
- 主要结局:平均每日吗啡毫克相当量 (MME) 和非阿片类药物处方率在2周,6周和3个月.
主要成果:
- 在实施后2周,平均每日MME显著下降,从19.59降至14.12 (p < 0.001).
- 在2周后,非阿片类药物处方率从59%增加到79% (p = 0.002).
- 在乙氨基和NSAID使用中观察到显著增加;在6周或3个月内没有显著差异.
结论:
- 在MLD患者中,阿片类药物节约途径有效地减少了阿片类药物的消费,并在早期术后期 (2周) 增加了非阿片类药物的使用.
- 该途径证明了成功的初始转向非阿片类药物疼痛管理.
- 长期使用阿片类药物的差异在2周以后并不显著,这表明持续的阿片类药物减少可能需要进一步的干预.
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