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Updated: Jun 16, 2025

Site Specific Lysine Acetylation of Histones for Nucleosome Reconstitution using Genetic Code Expansion in Escherichia coli
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第一个类别的除ubiquitinase向的奇美拉稳定和激活cGAS

Zhijie Deng1,2,3, Li Chen4,5, Chao Qian1,2,3

  • 1Mount Sinai Center for Therapeutics Discovery, Icahn School of Medicine at Mount Sinai, 10029, New York, New York, United States.

Angewandte Chemie (International ed. in English)
|August 16, 2024
PubMed
概括

新的双基因酶向嵌合体 (DUBTAC) 技术推进了向蛋白质稳定 (TPS). 研究人员为cGAS开发了新的DUBTAC,并改善了CFTR稳定,扩大了DUBTAC的应用.

关键词:
在 DUBTAC 里面,在OTUB1上.cGAS 是一个气体.有针对性的蛋白质稳定.这是一种瘤抑制剂.

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