在韩国COVID-19大流行之前和期间的儿科中毒模式的比较
Juho An1, Yura Ko1, Heewon Yang1
1Department of Emergency Medicine, Ajou University School of Medicine, Suwon, South Korea.
PloS one
|August 16, 2024
概括
在COVID-19期间,儿童中毒的急诊室访问增加了青少年和故意制药病例. 然而,预测模型表明,中毒模式的整体变化没有显著的变化.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 毒理学 毒理学 毒理学
背景情况:
- 在全球范围内,COVID-19流行病显著改变了寻求医疗保健的行为和疾病模式.
- 紧急诊所 (ED) 经历了患者人口统计和访问原因的变化,特别是在儿科和青少年群体中.
- 了解中毒病例中的这些变化对于公共卫生准备和反应至关重要.
研究的目的:
- 分析COVID-19大流行之前和期间儿童和青少年急诊室中毒访问的流行病学转变.
- 确定涉及的有毒物质类型和患者结果的变化.
- 评估大流行对年轻人中毒趋势的影响.
主要方法:
- 一项采用韩国基于ED的伤害深度监测 (2017-2021) 数据的横截面观察研究.
- 研究人群包括19岁以下的患者,有中毒.
- 数据被分为COVID-19前 (2017年1月至2020年2月) 和COVID-19 (2020年3月至2021年12月) 期间.
主要成果:
- 患者的平均年龄增加,在COVID-19期间青少年 (13-18岁) 显著增加.
- 蓄意中毒病例和药物中毒,特别是中枢神经系统 (CNS) 药物,显著增加.
- 贝叶斯结构时间序列 (BSTS) 模型表明,尽管观察到趋势,但故意儿童中毒病例的增加没有统计学上显著的增加.
结论:
- 虽然观察到的趋势表明,疫情期间有意中毒的增加,但BSTS预测模型显示,儿童中毒模式总体没有显著变化.
- 该研究强调了先进预测模型在准确评估危机中公共卫生趋势方面的重要性.
- 这些发现强调了针对青少年药物中毒的有针对性的干预措施的必要性.
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