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Updated: Jun 16, 2025

Identification of Specific Sensory Neuron Populations for Study of Expressed Ion Channels
11:34

Identification of Specific Sensory Neuron Populations for Study of Expressed Ion Channels

Published on: December 24, 2013

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一个对Nav和Cav通道的多功能残留物编号方案

Xueqin Jin1, Jian Huang2, Huan Wang1

  • 1Beijing Frontier Research Center for Biological Structures, State Key Laboratory of Membrane Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.

Cell chemical biology
|August 16, 2024
PubMed
概括

一个新的通用废物编号系统,用于电压关闭的 (Nav) 和 (Cav) 通道,有助于药物设计. 这种基于结构的方案有助于识别药物结合部位和疾病突变热点.

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Determination of the Relative Cell Surface and Total Expression of Recombinant Ion Channels Using Flow Cytometry11:32

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A proton...
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In the AX proton spin system, proton A can sense the two spin states of a coupled proton X, resulting in a doublet NMR signal with two peaks of equal (1:1) intensity. When proton A is coupled to two equivalent protons (AX2 spin system), the spin states of each X can be aligned with or against the external field, creating three possible scenarios. This results in a 1:2:1  triplet signal, where the central peak corresponds to the chemical shift of A and is twice as large or intense as the...
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In the late 19th-century, the number of new chemical compounds discovered increased tremendously. Hence, the necessity arose to develop a naming system for the systematic nomenclature of these newly discovered compounds. IUPAC (International Union for Pure and Applied Chemistry), established in 1919, sets rules for the nomenclature.
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When more than one substituent is present on the benzene ring, the IUPAC nomenclature depends on the number of substituents present.
For disubstituted benzene derivatives, with two groups attached to the benzene ring, three constitutional isomers are possible. For example, consider dimethyl benzene, often called xylene, where the second methyl group can be substituted at the second, third, or fourth carbon. The relative position of the substituents is represented by prefixes ortho, meta, or...
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