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Updated: Jun 16, 2025

Construction of Vapor Chambers Used to Expose Mice to Alcohol During the Equivalent of all Three Trimesters of Human Development
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Construction of Vapor Chambers Used to Expose Mice to Alcohol During the Equivalent of all Three Trimesters of Human Development

Published on: July 13, 2014

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在大鼠和子中对醇产前发育毒性研究

Wade Barranco1, Jefferson Fowles2, Erik K Rushton3

  • 1Lyondell Chemical Company, Houston, TX, USA.

Regulatory toxicology and pharmacology : RTP
|August 16, 2024
PubMed
概括

醇 (AA) 暴露不会导致老鼠或子的出生缺陷. 然而,在发育性毒性研究中观察到对母亲的毒性,导致妊娠流产增加和胎儿体重降低.

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相关概念视频

Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
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