代谢性疾病的全球负担,1990-2021年
Huai Zhang1, Xiao-Dong Zhou2, Michael D Shapiro3
1Department of Medical Record, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China; MAFLD Research Center, Department of Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Metabolism: clinical and experimental
|August 16, 2024
概括
代谢性疾病,如2型糖尿病和高血压,对全球健康构成越来越大的威胁. 分析显示,残疾调整寿命年数 (DALYs) 和死亡人数不断增加,迫切需要采取全球卫生行动.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 代谢疾病 代谢疾病
背景情况:
- 常见的代谢性疾病 (T2DM,高血压,肥胖,高胆固醇血症,MASLD) 构成了全球严重的健康负担.
- 从1990-2021年分析的趋势和负担使用了全球疾病负担 (GBD) 数据.
- 突出了代谢性疾病患病率的区域,时间和性别差异.
研究的目的:
- 分析1990年至2021年常见代谢性疾病的全球趋势和负担.
- 为了确定疾病影响的区域和时间变化.
- 为管理代谢性疾病的全球健康战略提供信息.
主要方法:
- 利用GBD 2021数据估计残疾调整寿命年 (DALY) 和死亡人数.
- 计算了每10万人口的年龄标准化DALY.
- 1990年至2021年间的估计年百分比变化 (APC) 用于趋势分析.
主要成果:
- 在2021年,高血压是最大的负担 (22600万DALY),其次是T2DM (7500万DALY).
- 在全球范围内,负担增加了1.6至3倍;T2DM和肥胖症呈现加速增长.
- 高血压和高胆固醇血症的负担正在减缓;MASLD没有显著变化.
结论:
- 代谢性疾病是21世纪全球卫生面临的主要挑战.
- 严重增加的DALY和死亡率需要协调的全球卫生倡议.
- 迫切需要采取行动,以减轻这些衰弱条件的影响.
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