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Updated: Jun 16, 2025

3D Multicolor DNA FISH Tool to Study Nuclear Architecture in Human Primary Cells
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3D Multicolor DNA FISH Tool to Study Nuclear Architecture in Human Primary Cells

Published on: January 25, 2020

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拓胺酶调节的全基因组DNA超圈域与核部位同位,并调节人类基因表达

Qian Yao1, Linying Zhu1, Zhen Shi1

  • 1Laboratory of Biochemistry and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

Nature structural & molecular biology
|August 16, 2024
PubMed
概括

研究人员开发了一种新的DNA超卷试验 (ATMP-seq) 来绘制全基因组超卷域的地图. 这揭示了DNA超级卷如何影响基因表达和染色体调节.

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