新生儿和婴儿大动脉血栓的管理:一个单中心病例系列
Ajibike Lapite1, Mohammad H Abu-Arja1, Hyojeong Han2,3
1Division of Hematology/Oncology, Department of Pediatrics, Baylor College of Medicine, Texas Children's Cancer and Hematology Center, Houston, Texas, USA.
Pediatric blood & cancer
|August 17, 2024
概括
新生儿大动脉血栓形成是婴儿罕见但严重的疾病. 涉及血栓溶解或血栓切除的治疗显示出积极的结果,并有可管理的并发症,建议在管理中考虑它们.
科学领域:
- 儿科 儿科 儿科
- 心血管医学 心血管医学
- 新生儿科学 新生儿科学
背景情况:
- 新生儿和婴儿大动脉血栓是罕见的,危及生命的疾病.
- 带有动脉导管的早产婴儿特别面临风险.
研究的目的:
- 描述新生儿/婴儿大动脉血栓瘤的机构经验和管理方法.
- 在这个人群中评估血栓溶解和血栓切除术的疗效和安全性.
主要方法:
- 对11名患有闭塞性或近闭塞性大动脉血栓症的婴儿进行了回顾性审查.
- 管理策略的分析,包括血栓消化疗法和抗凝药.
- 评估治疗结果和并发症.
主要成果:
- 所有11名婴儿都经历了至少部分血栓解脱.
- 在接受血栓溶解的两名患者中发生了轻微出血.
- 在仅接受抗凝药的患者中观察到两个主要出血事件.
结论:
- 在治疗新生儿/婴儿大动脉血栓症时,应考虑血栓溶解和血栓切除术.
- 这些干预措施在实现血栓解脱方面表现出有效性.
- 在治疗期间,必须仔细监测出血并发症.
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