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Updated: Jun 16, 2025

Design of a Biaxial Mechanical Loading Bioreactor for Tissue Engineering
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Design of a Biaxial Mechanical Loading Bioreactor for Tissue Engineering

Published on: April 25, 2013

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使用受约束反应混合理论建模软骨和纤维生物组织的疲劳失效

Brandon K Zimmerman1, Steve A Maas2, Jeffrey A Weiss2

  • 1Department of Mechanical Engineering, Columbia University, New York, NY 10027.

Journal of biomechanical engineering
|August 17, 2024
PubMed
概括

这项研究引入了一个计算框架,用于在长时间内模拟软组织的疲劳失败. 该模型基于反应动力学,准确地预测了组织损伤的进展,并有助于了解骨关节炎等慢性损伤.

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A Coupled Experiment-finite Element Modeling Methodology for Assessing High Strain Rate Mechanical Response of Soft Biomaterials

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相关概念视频

Fatigue01:21

Fatigue

Fatigue occurs when materials rupture under repeated or fluctuating loads, even at stress levels far below their static breaking strength. It typically results in brittle failure, even for ductile materials. It is a critical consideration in designing machines and structural components subjected to repetitive or varying loads. The nature of these loadings can range from fluctuating loads like unbalanced pump impellers causing vibrations to repeatedly bending a thin steel rod wire back and forth...
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