印度男性口腔粘膜癌的职业和风险:一个多中心病例控制研究
Romi Moirangthem1, Bayan Hosseini2, Aniket Patil1
1Division of Molecular Epidemiology and Population Genomics, Centre for Cancer Epidemiology, Tata Memorial Centre, Kharghar, Navi Mumbai, Maharashtra, India; Homi Bhabha National Institute (HBNI), Mumbai, Maharashtra, India.
Cancer epidemiology
|August 17, 2024
概括
某些职业,如工匠和机械操作员,与口腔粘膜癌 (BMC) 的更高风险有关. 减少职业暴露,并将烟草控制工作集中在这些群体上,可能有助于预防 BMC.
科学领域:
- 职业健康 职业健康 职业健康 职业健康
- 癌症流行病学癌症流行病学
- 公共卫生 公共卫生
背景情况:
- 口腔粘膜癌 (BMC) 是一个重要的健康问题,特别是在印度.
- 对于有针对性的预防策略来说,了解职业暴露在BMC发展中的作用至关重要.
研究的目的:
- 调查终身职业史与患口腔粘膜癌 (BMC) 的风险之间的关联.
主要方法:
- 一个多中心的,基于医院的病例控制研究进行了1969个BMC病例和2145个对照.
- 用面对面的面试来收集有关职业史的数据.
- 进行了后勤回归分析,以确定赔率比率 (OR) 和95%置信区间 (CI).
主要成果:
- 在"手工艺和相关行业工人" (OR 1.37;95% CI 1.13-1.65) 中观察到 BMC 风险增加.
- "工厂和机器操作员和组装人员" (OR 1.26;95% CI 1.01-1.56) 和"基本职业" (OR 1.33;95% CI 1.12-1.58) 也显示风险增加.
- 特定的高风险职业包括金属/机械工人,印刷工人,司机和建筑/制造工人.
结论:
- 某些职业与口腔粘膜癌的风险较高有关.
- 减少对危险职业病原体的暴露,并在高风险群体中实施有针对性的烟草控制措施,可以预防骨髓癌.
- 需要进一步的研究来确定特定的致病性暴露,并为预防工作提供信息.
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