双主动脉疾病患者心电图的预后值
Paul M Hendriks1, Zoë A Keuning1, Jan A Kors2
1Department of Cardiology, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, the Netherlands.
Journal of electrocardiology
|August 17, 2024
概括
电心电图 (ECG) 异常常见于双主动脉 (BAV) 患者. 电脑心电图上较长的PR间隔可能预测需要大动脉置换或在BAV个体中经历死亡的更糟糕的预后.
科学领域:
- 心脏病学 心脏病学
- 医学诊断 医学诊断 医学诊断
- 遗传学 是一个遗传学.
背景情况:
- 双动脉 (BAV) 是一种常见的先天性心脏缺陷.
- 识别患有心脏事件风险的患者至关重要.
- 在BAV患者中,心电图 (ECG) 的预后价值尚未得到充分确立.
研究的目的:
- 描述BAV患者的心电图参数.
- 为了研究心电图参数对BAV患者心脏事件的预后价值.
主要方法:
- 单中心前性研究.
- 包括120名没有先前进行大动脉置换 (AVR) 的BAV患者.
- 评估了ECG参数及其与所有原因死亡率和AVR的关联,使用Cox比例危险分析.
主要成果:
- 48%的BAV患者患有心电图异常.
- 经年龄调整后,较长的PR间隔与较差的无干预生存率相关 (HR1.02,95% CI:1.01-1.04).
- 其他异常包括QRS轴偏差 (14%) 和LVH (17%).
结论:
- 在BAV患者中,心电图异常很常见.
- 在BAV患者中,PR间隔可以作为无干预生存的预后标记.
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