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在达尔文温暖的小池的水中,生物进化已经死亡
Olen R Brown1, David A Hullender2
1Emeritus of Biomedical Sciences, At the University of Missouri, Columbia, MO, USA.
Progress in biophysics and molecular biology
|August 17, 2024
概括
由于必需的维生素和酶的同时共同产生,生命的起源是极不可能的. 当前的进化理论,包括适者生存理论,无法克服生物发生的这一基本挑战.
科学领域:
- 生物化学 生物化学
- 进化生物学 进化生物学
- 天体生物学 天体生物学
背景情况:
- 关于生命起源 (生物起源) 和其后来的进化的主流理论依赖于基因中心的新达尔文主义和自然选择.
- 自然选择或"最适者生存"被认为是推动进化变化的主要机制,并提供了方向性.
- 自然选择运作的关键先决条件是存在一种自我复制实体,例如第一个最小细胞.
研究的目的:
- 调查生物发生的概率性可行性,专注于从非生命过渡到第一个最小的活细胞.
- 评估重要的生化成分,特别是维生素和酶在生命起源中的共同起源的作用.
- 质疑"最适者生存"在解释自然条件下的生命初始组合的充分性.
主要方法:
- 利用概率计算来评估基本生化过程同时发生的可能性.
- 分析重点集中在关键的生物生成阶段,从非生物物质到第一个细胞.
- 在进化理论的背景下,研究了维生素和酶的共同进化需求.
主要成果:
- 需要的维生素和酶的同时共同产生,是生物发生的一个基本的,被忽视的障碍.
- 概率计算表明,这些重要生物化学成分的联合组装是荒谬的不太可能的.
- 即使有有利于进化论的假设,生命的起源仍然在统计学上不太可能,因为这个共同起源问题.
结论:
- 维生素和酶的共同起源构成了一个重要的概率障碍",适者生存"无法克服.
- 从非生命过渡到第一个最小细胞的可能性远远低于当前进化框架中经常假设的可能性.
- 这项研究表明,需要对生物起源模型进行批判性重新评估,强调生命起源的统计不可能性.
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