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双动脉患者感染性内心炎:独特的临床和微生物学特征

Juan A Quintero-Martinez¹, Joya-Rita Hindy², Hector I Michelena³

¹Division of Public Health, Infectious Diseases and Occupational Medicine, Department of Medicine, Rochester, MN, USA; Department of Cardiovascular Diseases, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.

Heart, lung & circulation

|August 17, 2024

概括

双主动脉 (BAV) 患者面临原生内心炎 (NVE) 和假内心炎 (PVE) 的风险. 了解它们独特的临床和微生物学特征对于有效的传染性内心炎 (IE) 诊断和管理至关重要.

科学领域:

心脏病学心脏病学
传染性疾病传染性疾病
膜心脏疾病膜心脏疾病

背景情况:

双动脉 (BAV) 是一种先天性心脏缺陷,与感染性内心炎 (IE) 的风险增加有关.
有限的数据存在于特定的临床表现和IE的微生物学在BAV.患者.
在BAV患者的本源与假体门中区分IE对于量身定制的治疗至关重要.

研究的目的:

在BAV.患者中描述本源内心炎 (NVE) 的临床特征.
为了比较BAV患者在BAV替换后患有假内心炎 (PVE) 的NVE.
确定与BAV相关的NVE和PVE相关的独特微生物特征.

主要方法:

从2008年至2021年,对被诊断患有IE和BAV的成年患者或有BAV替代史的回顾性分析.
用修改的杜克标准证实IE诊断;通过跨食道心声学证实BAV.
在NVE和PVE组之间对临床特征,微生物学和IE并发症的统计比较.

主要成果:

包括161名患者:60人患有NVE (37.3%) 和101人患有PVE (62.7%).
预发性肺炎患者年龄较大,并有更多的并发性疾病 (高血压,心力衰竭,脏疾病) 和周围.
在NVE患者中,隔离性中枢IE,中度至重度的大动脉吐和联合的大动脉-中枢IE的患病率较高. 杆菌疹在NVE中很常见,黄金葡萄球菌在PVE中很常见.

结论:

BAV患者对NVE和PVE都很敏感.
在BAV患者中,NVE和PVE呈现出明显的临床和微生物特征.
意识到这些差异对于优化IE诊断和患者管理至关重要.

关键词:

双主动脉门的双主动脉门内心内膜炎是一种内心内膜炎.微生物学微生物学结果的结果.假体门是一种假体门.

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