美国新诊断的COPD患者的治疗模式
Antonio Anzueto1, Sheri Rogers2, Bonnie Donato2
1South Texas Veterans Healthcare System, Division of Pulmonary Diseases/Critical Care Medicine, University of Texas Health, 111 E 7400 Merton Minter Blvd, San Antonio, TX, 78229, USA. anzueto@uthscsa.edu.
BMC pulmonary medicine
|August 17, 2024
概括
在美国,大多数新诊断的慢性阻塞性肺病 (COPD) 患者没有被处方维持疗法,导致大量恶化. 这项研究强调了COPD管理和遵守临床指南的关键差距.
科学领域:
- 肺部病理学 肺部病理学
- 药理学 药理学是指药理学的学科.
- 医疗保健服务研究 医疗服务研究
背景情况:
- 目前的指导方针建议对慢性阻塞性肺病 (COPD) 进行及时的维持治疗,以保持肺功能并防止恶化.
- 然而,这些建议与实际临床实践之间存在很大的差距,大多数患者在初始诊断时没有接受维持治疗.
- 这项研究调查了美国新诊断的COPD患者的治疗模式和结果.
研究的目的:
- 评估美国新诊断的COPD患者的药理治疗模式.
- 评估与这些治疗模式相关的结果,重点关注恶化.
- 识别关于COPD初始管理的临床实践指南的遵守情况.
主要方法:
- 一项回顾性,非干预性研究,利用来自Inovalon Insights数据库 (2015-2021) 的非识别数据.
- 在初始COPD诊断后4年的患者旅程的分析.
- 主要结局:中度或严重恶化的数量;次要结局:恶化的发生率,累计计数和治疗模式.
主要成果:
- 这项研究包括238,158名新诊断的慢性慢性病患者 (52.9%为女性,平均年龄为63.8岁),其中大多数受医疗补助 (46.2%) 保险.
- 大多数 (86.2%) 在诊断时没有接受治疗,63.8%在4年随访期间没有接受治疗.
- 尽管如此,32.9%的人至少经历过一次中度或严重的恶化;长效β-激动剂/吸入性皮质类固醇 (LABA/ICS) 是最常见的初始治疗 (62.0%).
结论:
- 在美国,大多数新诊断的COPD患者没有接受推的维持治疗.
- 这种缺乏治疗与中度至严重恶化的高发病率有关.
- 这些发现强调了与COPD管理的既定临床实践指南的显著偏离.
相关概念视频
01:29Chronic Obstructive Pulmonary Disease-V: Management
2.5K
Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation
Smoking Cessation
2.5K
01:26COPD: Management Using Bronchodilators and Corticosteroids
190
Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
190
01:20Chronic Obstructive Pulmonary Disease-I: Introduction
2.8K
Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
2.8K
01:22Chronic Obstructive Pulmonary Disease
1.2K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
1.2K
01:27Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
2.5K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
2.5K
01:20COPD: Pathogenesis and Clinical Features
246
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
246