与IBD相关的关节炎查问卷的挑战在早期和主要集中在肠道表现型中
Alen Zabotti1, Nicola Cabas2, Sofia Cacioppo2
1Division of Rheumatology, Department of Medicine (DMED), Azienda Sanitaria Universitaria Friuli Centrale (ASUFC), Rheumatology Institute, University of Udine, Piazzale Santa Maria Della Misericordia 15, 33100, Udine, Italy. zabottialen@gmail.com.
显著的5.6%的炎症性肠病患者患有未诊断的关节炎,主要是肠炎. 早期查对于及时诊断和管理这种常见的肠外表现是至关重要的.
科学领域:
- 胃肠病学 胃肠病学
- 类风湿病学 类风湿病学
- 临床流行病学临床流行病学
背景情况:
- 炎症性肠病 (IBD) 相关的关节炎是一种常见的肠外表现.
- 在IBD患者中早期发现未诊断的关节炎对于最佳管理至关重要.
研究的目的:
- 确定未被诊断的IBD相关关节炎的患病率和特征.
- 为了比较两个查问卷的有效性,DETAIL和IBIS-q,用于早期检测.
主要方法:
- 对177名IBD (克罗恩病和性结肠炎) 门诊患者进行了DETAIL和IBIS-q问卷调查.
- 对填写问卷的患者进行了盲目的风湿学评估.
- 排除了先前诊断为IBD相关的脊椎关节炎 (SpA) 的患者.
主要成果:
- 在5.6%的患者中新诊断出IBD相关的关节炎 (10/177).
- 肠炎是主要的模式 (80%),通常没有外围关节炎.
- 与IBIS-q相比,DETAIL问卷显示了更高的特异性 (84.4%),但敏感性较低 (40.0%),比IBIS-q (敏感性为70.0%,特异性为74.3%).
结论:
- 显著比例的IBD患者有未被诊断的关节炎.
- 肠道参与是早期IBD相关关节炎的关键特征.
- 查问卷应包括对象的参与,以改善早期检测.
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