高的甘油三指数与中年和老年中国人中风风险增加有关:一项全国纵向研究
Feifei Xu1, Yan Feng1, Xi Zhong2
1Department of Critical Care Medicine, West China Hospital, Sichuan University, No. 37, Guoxue Alley, Chengdu, 610041, People's Republic of China.
Scientific reports
|August 17, 2024
概括
甘油三糖 (TyG) 指数与中国老年人中风风险增加有关. 较高的TyG指数值与患中风的可能性更高相关,将其确定为一个重要的风险因素.
科学领域:
- 心血管研究研究心血管研究
- 代谢综合征研究 代谢综合征研究
- 流行病学 流行病学
背景情况:
- 脑卒中是一种严重的脑血管疾病,具有重大公共卫生影响.
- 了解可修改的风险因素对于中风预防策略至关重要.
研究的目的:
- 调查甘油三糖指数 (TyG) 与中风发病率之间的关联.
- 评估TyG指数作为中国中年和老年人中中风的独立风险因素.
主要方法:
- 利用了中国健康与退休长度研究 (2015年和2018年) 的数据.
- 使用后勤回归,趋势测试和子组分析来评估关联.
- 在非线性关系探索和倾向分数匹配 (PSM) 中应用限制立方线 (RCS),以控制混变量.
主要成果:
- 观察到TyG指数与中风风险之间存在正相关性.
- 限制性立方脊线分析表明,中风几率的增加趋势与TyG指数的上升有关.
- 在倾向得分匹配后,与TyG指数相关的中风完全调整的几率比为1.28 (95% CI:1.01,1.62).
结论:
- 甘油三糖指数 (TyG) 独立地与中风风险增加有关.
- 研究结果表明,TyG指数可以作为中年和老年中国人中风的有价值的预测生物标志物.
- 这凸显了对大脑血管健康的代谢参数监测的重要性.
相关概念视频
01:25Blood Studies for Cardiovascular System III: Serum Lipid Profile
141
Understanding serum lipids is crucial for maintaining cardiovascular health and preventing heart disease and stroke.
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
141
01:29Cholesterol: Significance and Regulation
523
Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...
Considering cholesterol and...
523