不常见的链球菌星座脑膜炎导致肺和脑干中风在一个免疫能力强的患者
Richard M Bresler1, Thomas Rabadi1, Joseph Kordsmeier1
1Department of Internal Medicine, Baptist Memorial Hospital - North Mississippi, Oxford, MS, USA.
The American journal of case reports
|August 18, 2024
概括
脑膜炎的罕见原因Streptococcus constellatus可以导致严重的并发症,如肺和脑干中风. 这一案例凸显了它的潜在病原性,即使在健康个体中也是如此.
科学领域:
- 医学微生物学 医学微生物学
- 神经学 神经学
- 传染性疾病 传染性疾病
背景情况:
- 链球菌,不包括肺炎链球菌,在非新生儿群体中是急性细菌性脑膜炎的不常见原因.
- 星杆菌星座 (Streptococcus constellatus) 是Streptococcus anginosus群的一部分,通常是一种在粘膜表面上发现的共生生物.
- 这种细菌可以变得致病,导致感染,特别是在粘膜损伤后.
研究的目的:
- 报告一个19岁的免疫能力强的男性病例,患有细菌性脑膜炎,肺,脑干中风由Streptococcus constellatus引起.
- 强调考虑Streptococcus constellatus作为严重感染的潜在病原体的重要性,包括神经复发症.
主要方法:
- 一个19岁的男性出现头痛和部疼痛的病例报告.
- 脑脊液和血液培养对Streptococcus constellatus呈阳性,通过矩阵辅助激光吸附脱离电离-飞行质谱的时间确定.
- 诊断成像包括肺的胸部CT和脑干梗的头部MRI.
主要成果:
- 患者出现脑膜炎症状,脑脊液和血液培养物呈阳性.
- 图像检测显示,肺部有显著的,以及脑干 (pons) 的急性心脏病发作.
- 患者接受了一轮静脉注射青素治疗,并没有出现神经缺陷而恢复.
结论:
- 在细菌性脑膜炎的情况下,应考虑Streptococcus constellatus作为潜在的致病因子.
- 罕见但严重的并发症,如脑干梗塞和肺部,可能由Streptococcus constellatus感染引起.
- 这些感染甚至可以发生在免疫能力强的个体中,需要高度的怀疑指数.
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