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纵向模型的视觉预测检查和掉队的预测检查.

Chuanpu Hu1, Anna G Kondic2, Amit Roy3

  • 1Clinical Pharmacology, Pharmacometrics & Bioanalysis, Bristol Myers Squibb, 3551 Lawrenceville-Princeton Road, Lawrenceville, NJ, 08540, USA. chuanpu.hu@bms.com.

Journal of pharmacokinetics and pharmacodynamics
|August 18, 2024
PubMed
概括

视觉预测检查 (VPCs) 可以通过在临床试验中考虑患者退出来改进. 使用基于观察数据的置信区间的有条件方法,可以比传统方法更有效地评估药理学模型.

关键词:
疾病进展 疾病进展.放弃 放弃 放弃 放弃有关信息的审查信息审查.非线性混合效应模型时间变化的共变量.

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