在患有单侧鼻眼道阻塞的患者中出现更高阶异常
Melek Mutlu Sönmez1, Emine Savran Elibol2, Fatma Sali3
1Department of Ophthalmology, Göztepe Prof. Dr. Süleyman Yalçın City Hospital, Istanbul, Turkiye.
Korean journal of ophthalmology : KJO
|August 18, 2024
概括
主要获得的鼻管阻塞 (PANDO) 可以导致角膜高阶异常 (HOA) 的增加. 这些异常与发症的严重程度相关,影响受影响眼睛的视力.
科学领域:
- 眼科医生 眼科 眼科
- 角膜生理学 角膜生理学
- 视觉科学科学 视觉科学
背景情况:
- ,或过度流,是一种常见的症状,可以显著影响患者的生活质量.
- 主要获得的鼻管阻塞 (PANDO) 是的常见原因,特别是在老年人中.
- 尚不清楚PANDO对角膜光学,特别是更高阶异常 (HOA) 的影响.
研究的目的:
- 为了调查和比较由于单边PANDO而经历发症的患者的角膜高阶异常 (HOAs).
- 评估这些患者的同伴 (未受影响) 眼睛进行比较.
- 探索PANDO症状的严重程度和测量的角膜HOA之间的关系.
主要方法:
- 研究了一组61名患者 (122只眼睛) 的单边PANDO.
- 用Sirius地形测量角膜地形和HOA.
- 蒙克分数和光素染料消失测试 (FDDT) 用于量化PANDO严重性.
主要成果:
- 与其他眼睛相比,单侧PANDO患者的平均昏迷状异常 (0.19对0.10,p=0.03) 和角膜总HOA (0.30对0.23,p=0.04) 显著高.
- 在Munk分数和昏迷样异常 (r=0.53,p=0.003) 和总HOA (r=0.44,p=0.010) 之间发现了正相关性.
- FDDT等级还显示了与昏迷样异常 (r=0.48,p=0.001) 和总HOA (r=0.33,p=0.001) 的正相关性.
结论:
- 单边PANDO与受影响眼睛的角膜HOA增加有关.
- 根据Munk评分和FDDT的指标,和眼聚集的严重程度与角膜HOA的程度呈正相关性.
- 这些发现表明,PANDO可以诱导或加剧角膜异常,可能导致视力障碍.
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