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相关概念视频

Cancer Therapies02:49

Cancer Therapies

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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
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Therapeutic Index01:13

Therapeutic Index

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The therapeutic index of a drug is a key parameter in pharmacology that quantifies the relative safety of a drug by calculating the ratio between the dose that causes toxicity in half the population (50%) to the dose that proves to be effective for half the population (50%). It provides a spectrum of doses for a particular drug ranging from effective to potentially toxic. To illustrate, consider an anticoagulant agent like warfarin. It possesses a narrow window within its therapeutic index to...
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Targeted Cancer Therapies02:57

Targeted Cancer Therapies

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
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Heart Failure Drugs: Inotropic Agents01:26

Heart Failure Drugs: Inotropic Agents

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Positive inotropic agents are commonly used as the first line of treatment for heart failure. One such agent is digoxin, derived from the genus Digitalis, which has been known for centuries but effectively utilized since 1785. However, these cardiac glycosides can have potentially toxic effects due to their mechanism of action, which involves inhibiting Na+/K+-ATPase and increasing contractility. Digoxin is absorbed orally and distributed in various tissues, including the CNS. It has a long...
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Direct-Acting Cholinergic Agonists: Therapeutic Uses01:11

Direct-Acting Cholinergic Agonists: Therapeutic Uses

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Direct-acting cholinergic agonists have many therapeutic uses in various medical fields. Choline esters, including acetylcholine, have limited clinical utility due to their non-selectivity and short duration of action. Still, acetylcholine and carbachol are applied topically during ophthalmologic surgery to induce miosis. Pilocarpine, a muscarinic and ganglionic stimulator, effectively treats open-angle glaucoma and alleviates xerostomia and dry mouth caused by radiotherapy or Sjögren...
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Tumor Immunotherapy01:27

Tumor Immunotherapy

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Operating Procedures of the Electrochemotherapy for Treatment of Tumor in Dogs and Cats
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Operating Procedures of the Electrochemotherapy for Treatment of Tumor in Dogs and Cats

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化学疗法在马匹实践中的化学疗法

Fernando Malalana1

  • 1Philip Leverhulme Equine Hospital, University of Liverpool, Leahurst Campus, Chester High Road, Neston CH64 7TE, United Kingdom.

The Veterinary clinics of North America. Equine practice
|August 18, 2024
PubMed
概括

细胞毒性化疗药物治疗马类皮肤瘤局部或内溶性. 由于严重的副作用及其致癌性质,应极其谨慎地处理这些强效药物.

科学领域:

  • 兽医医学 兽医医学 兽医医学
  • 在瘤学瘤学.
  • 药理学 药理学是指药理学的学科.

背景情况:

  • 化疗利用细胞毒药物来消除癌细胞.
  • 马的全身化疗主要用于淋巴瘤.
  • 细胞毒药物经常用于可访问的马皮肤瘤.

研究的目的:

  • 概述马类皮肤病学中细胞毒药物的使用情况.
  • 突出这些药物的施用方法和安全预防措施.

主要方法:

  • 细胞毒药膏的局部应用.
  • 细胞毒性药物的内侧注射.
  • 对处理细胞毒剂的安全协议的审查.

主要成果:

  • 细胞毒药物对治疗容易接触到的马皮肤瘤是有效的.
  • 给药途径包括局部和内溶性方法.
  • 显著的副作用风险需要小心处理.

结论:

  • 细胞毒药物在马类皮肤瘤治疗中非常有价值.
  • 在制备,处理,管理和处置过程中,严格的安全措施至关重要.
关键词:
化疗 化疗是一种化学疗法.细胞毒性 细胞毒性马马的马,就是马马.瘤是一个瘤.

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  • 这些药物的致癌性,致变性和致病性潜力需要高度谨慎.