社会的脆弱性和产前诊断
Insaf Kouba1,2,3, Jaclyn Del Pozzo1,2,3, Alejandro Alvarez1,4
1Northwell, New Hyde Park, NY, USA.
Journal of perinatal medicine
|August 19, 2024
概括
社区的社会脆弱性不会影响产前诊断率. 这项研究发现,孕妇患者的社会脆弱性指数 (SVI) 和产前诊断程序之间没有关联. 在不同的人群中可能需要进一步的研究.
科学领域:
- 生殖健康 生殖健康
- 公共卫生 公共卫生
- 遗传咨询 遗传咨询
背景情况:
- 关于影响产前诊断率的社区风险因素的数据有限.
- 社会脆弱性指数 (SVI) 量化了影响健康的累积环境压力因素.
- 了解SVI的作用对于公平获得产前护理至关重要.
研究的目的:
- 确定社会脆弱性指数 (SVI) 和产前诊断之间的关系.
- 分析SVI对接受遗传咨询的孕妇患者的影响.
- 评估产前诊断决策中的社区级社会经济因素.
主要方法:
- 在纽约接受遗传咨询的5935名孕妇患者 (2019-2022) 的回顾性队列研究.
- 将患者居住地与基于人口普查通道的社会脆弱性指数 (SVI) 得分联系起来.
- 使用多变量逻辑回归来分析主要结果:产前诊断 (是/不是).
主要成果:
- 在SVI和产前诊断之间没有观察到统计学上显著的关联.
- 与增加产前诊断相关的因素包括说英语,遗传疾病携带者身份,增加NT,异常NIPS和胎儿结构异常.
- 没有发现基于种族,种族,保险或婚姻状况的诊断率有显著差异.
结论:
- 社会脆弱性指数 (SVI) 似乎没有影响纽约人口的产前诊断率.
- 研究结果表明,除了邻居的社会脆弱性之外,其他因素与产前诊断程序更为密切相关.
- 需要在不同地理区域和不同的人口群体进行进一步的研究来证实这些发现.
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